The Longevity Benefits of NAD+

Longevity is a topic that has fascinated people for centuries, and it seems that as humans continue to live longer, the search for ways to extend life only intensifies. One promising area of research in the quest for longevity is the molecule NAD+.

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells. It plays a crucial role in energy metabolism and is involved in a wide range of physiological processes, including DNA repair, gene expression, and neurotransmitter synthesis.

How does NAD+ affect longevity?

One of the most exciting findings in the field of aging research is the discovery that NAD+ levels decline with age. This decline is thought to be a major contributor to age-related diseases and the overall decline in cellular function that occurs as we get older. By boosting NAD+ levels, it may be possible to delay or even reverse some of the negative effects of aging.

There is evidence to suggest that increasing NAD+ levels can have a number of beneficial effects on health and longevity. For example, animal studies have shown that increasing NAD+ levels can improve insulin sensitivity, lower blood pressure, and reduce inflammation. Other research has found that NAD+ supplements can increase lifespan in certain organisms, such as yeast and worms.

There are also studies that suggest NAD+ may have anti-aging effects in humans. One small study found that taking NAD+ supplements led to improvements in skin health, including increased hydration and elasticity. Another study found that NAD+ supplements improved cognitive function in elderly individuals. While these findings are preliminary and more research is needed, they suggest that increasing NAD+ levels could have a number of potential benefits for health and longevity.

How can NAD+ levels be increased?

There are several ways to increase NAD+ levels in the body. One way is through diet. Foods that are high in NAD+ precursors, such as tryptophan and niacin (vitamin B3), can help boost NAD+ levels. Some research has also found that calorie restriction, which involves reducing calorie intake while still getting enough nutrients, can increase NAD+ levels and improve overall health.

Another way to increase NAD+ levels is through supplementation. There are a number of NAD+ supplements on the market, which can be taken in the form of capsules, tablets, or intravenous infusions. While more research is needed to determine the optimal dosage and long-term safety of NAD+ supplements, some studies have found them to be effective at increasing NAD+ levels in the body.


Overall, the research on NAD+ and longevity is still in the early stages, but the findings so far are promising. By boosting NAD+ levels, it may be possible to delay or even reverse some of the negative effects of aging and improve overall health. While more research is needed to fully understand the role of NAD+ in aging and to determine the optimal way to increase NAD+ levels, the potential benefits of NAD+ for longevity are certainly worth exploring.